I know this sounds ridiculous, but I believe Loy-Chi can actually win the national championship. I doubt they will, but this may be the first time a seed this low has a real legit shot at doing it. Would have to go over the champion teams list to see who was not in the Big Boys' club (ie, Duke, Kansas, UNC, UK, etc, etc)
You could probably go over the last 20 champions and they're all in the Big Boy's club.